Aging is associated with impairment of sensorial functions and with the onset of neurodegenerative diseases.As pari passu circulating insulin-like growth factor 1 (IGF-1) bioavailability progressively decreases, we see a direct correlation with sensory impairment and cognitive performance in older humans.Age-related sensory loss is typically caused
Sensory inputs in nervous systems are often encoded at the millisecond scale in a precise spike timing code.There is now growing evidence in behaviors ranging from slow breathing to rapid flight for the prevalence of precise timing encoding in motor systems.Despite this, we largely do not know at what scale timing matters in these circuits due to t
In connection with the Year of Literature in Russia which started in January 2015 the author shows the importance of legacy of world and Russian literature and points out the role of literature in society.The author answers the question what literature means for the development of human culture.On the basis of thesaurus approach the author Outdoor
Normal and pathological processes entail the production of oxidative substances that can damage biological molecules and harm physiological functions.Organisms have evolved complex mechanisms of antioxidant defense, and any imbalance between oxidative challenge and antioxidant protection can depress fitness components and accelerate senescence.Whil
The Waterhouse-Friderichsen Syndrome (WFS) is a pediatric emergency characterized by high mortality due to the combination of bilateral adrenal haemorrhage, meningococcal infection and cutaneous purpura.WFS often raises medico-legal problems related to missed or delayed diagnosis mainly related to the short clinical course, the sudden onset of symp